Quantitative contrast-enhanced optical coherence tomography
نویسندگان
چکیده
منابع مشابه
Quantitative contrast-enhanced optical coherence tomography.
We have developed a model to accurately quantify the signals produced by exogenous scattering agents used for contrast-enhanced Optical Coherence Tomography (OCT). This model predicts distinct concentration-dependent signal trends that arise from the underlying physics of OCT detection. Accordingly, we show that real scattering particles can be described as simplified ideal scatterers with modi...
متن کاملContrast-enhanced intraoperative optical coherence tomography.
Optical coherence tomography (OCT) has revolutionised clinical ophthalmology. The translation of OCT into the operating room is a natural next step given its high-resolution anatomic information. Contrast agents and enhancement have significantly improved the diagnostic capabilities of numerous imaging modalities (such as CT and MRI). The use of OCT contrast agents in ophthalmology has been gen...
متن کاملMagnetic contrast agents for optical coherence tomography
The magneto-mechanical effect is exploited as a means of producing background-free contrast in optical coherence tomography (OCT). Contrast agents consisting of iron-oxide particles and protein microspheres encapsulating colloidal iron-oxide have a sufficiently high magnetic susceptibility to be detected by modulation of a magnetic field gradient using a small solenoid coil. The externally-appl...
متن کاملMolecular contrast optical coherence tomography: a review.
This article reviews the current state of research on the use of molecular contrast agents in optical coherence tomography (OCT) imaging techniques. After a brief discussion of the basic principle of OCT and the importance of incorporating molecular contrast agent usage into this imaging modality, we shall present an overview of the different molecular contrast OCT (MCOCT) methods that have bee...
متن کاملContrast enhancement in optical coherence tomography
Molecular imaging is a powerful tool for studying disease progression and potential therapies in animals. Optical coherence tomography (OCT) is an important biomedical imaging modality, filling the niche between ultrasound and microscopy. However, OCT suffers from an inherent lack of molecular contrast (the ability to distinguish a molecule of interest from others). This is because the scatteri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Applied Physics Letters
سال: 2016
ISSN: 0003-6951,1077-3118
DOI: 10.1063/1.4939547